For the month of 6/1/2001
DHEA
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PROPER NAME:
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Dehydroepiandrosterone
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COMMON NAMES:
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DHEA
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FORMS:
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Tablets or capsules ranging in doses from 25 mg to 50 mg
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MARKETING CLAIMS:
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“Eternal youth - Offsets aging process by enhancing vitality, memory and libido.”
“Enhances the immune system.”
“Many diseases just melt away-including heart disease, cancer, Alzheimer’s disease, lupus, and AIDS.”
“Weight-loss aid”
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DOSAGE:
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Numerous studies have used doses ranging from 0.1 mg/kg body weight to 1000mg/kg body weight. Most of the effects of DHEA supplementation have been extrapolated from epidemiological or animal studies and still need to be researched in humans.
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SIDE EFFECTS:
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Acne, hair loss and/or excessive hair growth, deepening voice in women (may be irreversible), increased growth of prostate, breast, and ovarian cancers.
The long-term consequences of DHEA supplementation are unknown, and the potential adverse effects may outweigh the possible benefits. Until more research is available on the safety, efficacy and dosage of DHEA, supplementation is not recommended.
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RESEARCH FINDINGS:
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As you get older serum DHEA levels decline, the research thus far shows no evidence that supplementation prevents aging. Research also shows that there is no correlation between decreased DHEA levels and cognitive function, nor is there enough evidence to say that DHEA improves memory, mood, and libido. DHEA supplementation claims to enhance the immune system, however the results are conflicting. Epidemiological and animal studies on the effects of heart disease and cancer also show conflicting results. Preliminary trials done on patients with lupus have shown some decrease in disease activity, however more research is needed before any recommendations can be made. Overall, there is no overwhelming evidence to show that DHEA supplementation is effective or safe. Until more research is done, DHEA supplementation is not recommended.
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DHEA REFERENCES:
Sarubin, A. The Health Professional’s Guide To Popular Dietary Supplements.
The American Dietetic Association. 104-112 (1999).
Integrative Medicine: Herb & Dietary Supplement Report.
Dehydroepiandrosterone’s (DHEA) Effects on Immunity and Life Span. November 1999. Pg.3.
Disclaimer:
This article is intended to provide basic information only. It is not a recommendation for use or endorsement of any product listed, by the Southeastern Michigan Dietetic Association. Please consult your physician or a health professional before taking any medications or supplements.
Looking for previously posted Complementary Nutrition topics or our Cultural Food Pyramids and Recipes? Visit our archives in the
General Nutrition Information Section.
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